Wang resin swelling

Wang resin swelling. 3. 09. , Wang, J. Composites Science and Technology 2024, 248 , 110442. Lyophilize the fina l material and did LC- MS to 2. While much research has been directed toward the optimization of linker groups for the attachment of compounds to the polymer, the development of new polymers themselves has been relatively neglected. Aldrich-13618; Wang resin extent of labeling: 0. The swelling agents were respectively selected as formic acid, acetic acid, oxalic acid, ethanol, and acetone. 49. , et al. https 855122 Sigma-Aldrich NovaPEG Wang resin. [2] Prepared from a low load Wang resin, to help facilitate the synthesis of longer peptides. Transfer resin to the vessel. 0 mmol/g loading; Synonyms: p-Alkoxy-benzyl alcohol polymer-bound; p-Alkoxybenzyl alcohol resin; [4-(Hydroxymethyl)phenoxymethyl]polystyrene; find related products, papers, technical documents, MSDS & more at Sigma-Aldrich. Fang Wang's 6 research works with 102 citations and 1,477 reads, including: Modification mechanism of C9 petroleum resin and its influence on SBS modified asphalt Colour (visual): white to yellow to beige Appearance of substance (visual): beads Loading (Photometric determination of the Fmoc-chromophore liberated upon treatment with DBU/DMF): 0. 070 Corpus ID: 34369014; Synthesis and swelling behaviors of carboxymethyl cellulose-based superabsorbent resin hybridized with graphene oxide. Colour (visual): white to light yellow to beige Appearance of substance (visual): beads Loading (determined from the substitution of the Fmoc-Leu loaded resin): 0. 0 mL g −1 a moderate solvent and less than 2. These relatively mild cleavage conditions have made this resin popular also in solid phase organic synthesis. Overall, the choice of Colour (visual): white to light yellow to beige Appearance of substance (visual): beads Loading (determined from the substitution of the Fmoc-Leu loaded resin): 0. 00 mmol/g Enantiomeric purity: ≥ 99. Author links open overlay panel Zhimin Wang a, Aimin Ning a, 2016, Wang and Wang, 2010). The swelling properties of microfluidic-droplet-designed resins and conventional TG ® resin as a control resin were evaluated in various solvents (Fig. 30 mmol/g: Swelling Volume (in DMF) lot specific result: Swelling Volume (in CH₂Cl₂) lot specific result: Total swelling volume acc. After resin 3. 2 ml/g Total swelling volume acc. 39%-157. 4. 00 mmol/g Swelling Volume (in DMF): lot specific The solid-state resin has good physical properties. Sci. 8%, A superabsorbent resin (SAR) with good degradability was prepared with acrylic acid (AA), acrylamide (AM), 2-acrylamido-2-methylpropane sulfonic acid (AMPS), organic montmorillonite (OMMT) and 855122 Sigma-Aldrich NovaPEG Wang resin. The higher the percentage of cross linkage with DVB, the lower the swelling is in a specific solvent. 5 % (a/a) Swelling Volume (in DMF): lot specific The qualitiy of this resin has been confirmed by the successful synthesis of the 21mer peptide related to myelin oligodendrocyte glycoprotein (35-55), with an Fmoc-Val-Wang resin made from the same batch of base resin. If it is not effective use ultrasonic and/or add minimum volume of DMF. The most commonly used esterification process is This pre-loaded Wang resin is prepared using a synthesis-tested base resin, to ensure reproducibility and efficacy in SPPS. carbpol. The results reported herein reveal that the swelling method followed by us can be effectively used to improve the interfacial bonding strength between the fibers and the resin matrix. 5 % (a/a) Swelling Volume (in DMF): lot specific Wang resin (p-alkoxybenzyl alcohol resin or 4-(hydroxymethyl)-phenoxymethyl (linker)) The amount of swelling depends on the density of the residue component, and, therefore, it does make a difference at which reaction char is former, and in what quantities, where this is an significant, if the studied process was considered at the large This pre-loaded Wang resin is prepared using a synthesis-tested base resin, to ensure reproducibility and efficacy in SPPS. However, The qualitiy of this resin has been confirmed by the successful synthesis of the 21mer peptide related to myelin oligodendrocyte glycoprotein (35-55), with an Fmoc-Val-Wang resin made from the same batch of base resin. 6% and 78. (1996) Tetrahedron Lett . 00 mmol/g Enantiomeric purity: ≥ 95. 45 mmol/g Enantiomeric purity: lot specific result Swelling Volume (in DMF): lot specific result Identity (of the substitution): passes test The polymer matrix is copoly (styrene-1% DVB), 100 - 200 mesh. 48-56 Zhimin Wang , , Andong Song This pre-loaded Wang resin is prepared using a synthesis-tested base resin, to ensure reproducibility and efficacy in SPPS. Efficient degradation of amine cured epoxy resin via the cleavage of C-N bond by amphiphilic dodecylbenzenesulfonic acid. Authors Dan Zheng 1 , Kai Wang 2 , Bo Bai 3 , Na Hu 4 , Honglun Wang 4 Acrylic Resins / chemistry* The swollen resin was compressed with the piston of the syringe, and the pressure was slowly released. For 100 mg of peptide-resin, mix 250 uL of ethanedithiol, 50 uL of m Fmoc-Ile-Wang resin LL (100-200 mesh) Novabiochem®; find Sigma-Aldrich-856111 MSDS, related peer-reviewed papers, technical documents, 0. Wang Resin Wang resin is the standard peptide synthesis resin used with Fmoc-chemistry. Preparation, Swelling Behaviors and Fertilizer-Release Properties of Sodium Humate Modified DOI: 10. The overuse of swelling agents in fruits and vegetables has rapidly increased, resulting in food safety problems. , Wang, Z. However, if the cross-linking degree is too low, the swelling is too large, it is not easy to filter, and the mechanical properties are not good and easy to break. Close menu Fmoc-AA Wang Resin. Accurately weight the Rink amide resin or pre-loaded Wang resin into the reaction vessel. Allow the solvent to percolate slowly through the resin bed. Please contact AAPPTec for a In this study, the solid-phase synthesis of Fmoc-N-Me-AA-OH was developed, comparing methylation with dimethyl sulfate or with methyl iodide. 5 % (a/a) Fmoc-Lys(ivDde)-Wang resin (100-200 mesh) has been used as a solid support to prepare a peptide bearing a hexacarbonyldiiron cluster, 0. }, author={Zhimin Fmoc-Ala-Wang resin LL (100-200 mesh) Novabiochem® at Sigma-Aldrich 0. , Yong, D. Kejian Wang * Institute of As it does inside the capillary, the swelling evolves with time outside the capillary to reach a maximum at a certain extrusion distance. 7 resulting mixture was shaken vigorously for 1 hour, followed by microfiltration and washes (5 x 2 volumes per bed volume). 69%, respectively. 12. 111823 Corpus ID: 255654811; Recycling of ammonia-cured epoxy resin by oxidative degradation of nitric acid assisted by swelling agent @article{Zhang2023RecyclingOA, title={Recycling of ammonia-cured epoxy resin by oxidative degradation of nitric acid assisted by swelling agent}, author={Xiongfei Zhang and Chuang Colour (visual): white to light yellow to beige Appearance of substance (visual): beads Loading (determined from the substitution of the Fmoc-Leu loaded resin): 0. 2. ≥ 98. Epub 2022 Jan 11. These fall into three broad categories: 1. Houben Buy wang resin for peptide synthesis at best price with Applied Polytech. COMPOSITESB. In addition, we outline the recently developed resins with the Rink, Ramage and Sieber handles. The commercial Wang 855122 Sigma-Aldrich NovaPEG Wang resin. 0. 015 Corpus ID: 139927216; Preparation, swelling behaviors and fertilizer-release properties of sodium humate modified superabsorbent resin @article{Yu2019PreparationSB, title={Preparation, swelling behaviors and fertilizer-release properties of sodium humate modified superabsorbent resin}, author={Xianglin Yu and Wang Fmoc-Phe-Wang resin (100-200 mesh) View Price and Availability. The sample recovered after the swelling treatment was named swollen-EP. The 2-chlorotrityl chloride resin (2-CTC resin) was employed as a temporary protecting group for the carboxylic acid strategy. 100-200 Mesh, 1% DVB, 0. 117 Table 5-4: Different types of solvent systems for Merrifield resin and values of each solvent ’s Hansen Wang Resin | C15H16O2 | CID 2734007 - structure, chemical names, physical and chemical properties, classification, patents, literature, biological activities, safety Hansen solubility parameter (HSP) space could be used to define high, medium and low swelling regions for each resin. 00 mmol/g Swelling Volume (in DMF): lot specific result Identity (of the substitution): passes test The polymer matrix is copoly (styrene-1 % DVB), 100 - 200 mesh. Supelco. Swelling test. 3 mL g −1) and a similar level of swelling is observed if a single amino acid is attached (23). 109230 Corpus ID: 238672717; Recycling of carbon fiber-reinforced epoxy resin composite via a novel acetic acid swelling technology @article{Xing2021RecyclingOC, title={Recycling of carbon fiber-reinforced epoxy resin composite via a novel acetic acid swelling technology}, author={Mingfei Xing and Zixin Li and Guohang 4-methylbenzhydrylamine Hydrochloride Salt Resin (MBHA resin) MBHA resin is used in the synthesis of peptide amide by Boc chemistry. Use 2 eq of Fmoc-AA and 4 eq of DIPEA. MTCOMM. Ammonium acetate. 0 equivalent based on the chlorine substitution of the resin). 5 % (a/a) Swelling Volume (in DMF): lot specific There are a wide variety of linkers for polystyrene core resins, such as Wang and Rink. Color (visual): white to slight yellow to beige Appearance of substance (visual): beads Loading (Photometric determination of the Fmoc-chromophore liberated upon treatment with DBU/DMF): 0. In today’s post, I’ll evaluate several conditions suitable for efficiently loading the first amino acid onto Wang-type resin. ≥ 99. 3-0. 40 mmol/g Enantiomeric purity: lot specific result Swelling Volume (in DMF): lot specific result Identity (of the substitution): passes test The polymer matrix is copoly (styrene-1 % DVB), 100 - 200 mesh. 5 % (a/a) Swelling Volume (in DMF): lot specific Color (visual): white to slight yellow to beige Appearance of substance (visual): beads Loading (Photometric determination of the Fmoc-chromophore liberated upon treatment with DBU/DMF): 0. Add the dry carboxylic acid cesium salt (1. 4 mL. Leznoff [1] was the first to demonstrate the utility of such resins in solid phase synthesis with the preparation of mono-acylated diamines from symmetrical diamines. Keywords UHMWPE fiber · Swelling method · Fiber reinforced resin matrix composites · Interface Introduction @article{Tian2020EnergyEfficientCO, title={Energy-Efficient Conversion of Amine-Cured Epoxy Resins into Functional Chemicals Based on Swelling-Induced Nanopores}, author={Fei Tian and Xiong-lei Wang and Yang Yang and Wenli An and Xu Zhao and Shimei Xu and Yu-Zhong Wang}, journal={ACS Sustainable Chemistry \& Engineering}, year={2020}, The resin swelling phenomenon could benefit the penetration of catalysts so as to accelerate the reaction of degradation (Wang et al. , Wu, W. Fmoc protected amino acids are linked to Polystyrene-PHB (Wang resin, consisting of 1% crosslinked polystyrene functionalized with the TFA labile p-benzyloxybenzyl alcohol linker). 50 mmol/g Swelling Volume (in DMF): lot specific result Swelling Volume (in CH₂Cl₂): lot specific result Total swelling volume acc. The standard procedures described here (see Subheading 3. , Mei, H. 5 % (a/a) Swelling Volume (in DMF): lot specific result Identity (of the substitution): passes test Content Dipeptide (HPLC): ≤ 0. Its use in SPPS enables the efficient and rapid Typically, the protocol involves swelling the Wang chlo-ride resin (2,1g; 1 mmol) in DMF (10 ml), reacting it with the Fmoc-amino acid (3 mmol), potassium iodide (0. et al. DMF, Weighing and Swelling the Resin. This support is more acid sensitive than BHA resin, and thus allow release of the Hydrogen bond formation between CEP and acetic acid is one of the important causes of resin swelling. 5 % (a/a) Swelling Volume (in DMF): lot specific Prepared from a low load Wang resin, to help facilitate the synthesis of longer peptides. The resin is acid labile and finished peptides can be easily cleaved by treatment with 50 % (v/v) TFA/DCM. Filter Filter. Similarly, Dressman, et al. , Liu, J. However, commercially available Fmoc-N-Me-AA-OHs are limited and often expensive. studied synthesis and swelling behaviors of carboxymethyl cellulose-based superabsorbent resin hybridized with graphene oxide (Wang et al. 8%, respectively. Excessive swelling of CEP in DMAC resulted in the cracking of the resin matrix between the adjacent carbon fiber layers. 39% and 0-0. 119113. Price A superabsorbent resin (SAR) with good degradability was prepared with acrylic acid (AA), acrylamide (AM), 2-acrylamido-2-methylpropane sulfonic acid (AMPS), organic montmorillonite (OMMT) and 1073 – Wang Resin for Peptide Synthesis with Fmoc-Amino Acids; 1034 – Fmoc-Amino Acid Wang Resins; 1113 – HMPA Resin Preparation, Coupling and Cleavage; 1183 – Preparing Low-Loading Fmoc-Amino Acid Wang Resins From High Substitution Wang Resin; 1074 – Weinreb Resin for Solid Phase Synthesis of Peptide Aldehydes The thermody namic analysis indicated that the swelling process is an exothermic process. Fang Wang's 6 research works with 102 citations and 1,477 reads, including: Modification mechanism of C9 petroleum resin and its influence on SBS modified asphalt Semantic Scholar extracted view of "Synthesis and swelling behaviors of sodium carboxymethyl cellulose-g-poly (AM), a novel super absorbent resin (SAR) of soluble Expand. 1). 1. 5. 2023. 2010), which is prepared by polymerization of compounds containing hydroxyl group, carboxyl group, sulfonic group, amide group, and other strong hydrophilic Wang resin (100-200 mesh) CAS 65307-53-1 Novabiochem® - Find MSDS or SDS, a COA, data sheets and more information. Chizhou Wang, Ning Zhang, Shaodi Wu, Weijie Wang, Peng Zhao, Shiyu Jia, Yongqin Qi, Xianglin Hou, Xiaojing Cui, Tiansheng Deng. []. Certain amino acids can cause problems during TFA cleavage and deprotection. resin swelling behavior in the course of SPS will be proposed. 00 mmol/g Swelling Volume (in DMF): lot specific DEGDMA–PS–Wang resin and TEGDMA–PS–Wang resin were used as the solid-phase support for the synthesis of a difficult sequence, the fragment of acyl carrier protein 65–74. Swelling Volume (in DMF): lot specific result Identity This pre-loaded Wang resin is prepared using a synthesis-tested base resin, to ensure reproducibility and efficacy in SPPS. The Wang resin is manufactured starting from a Swelling profi le of PuroSynthTM the last step is the cleavage and precipitation of Kalata B2 from wang resin with cocktail - K and diethyl- ether. For hydroxymethyl-based resins 4 to 6, formation of the ester linkage is easier with unhindered resins such as Wang resin 4 compared with resins possessing withdrawing methoxy groups 5 and 6. Cleavage conditions for the ester anchor involve concentrated TFA or TFA/CH₂Cl₂ to provide carboxylic acids or cyclization-cleavage under acidic or basic conditions. 18. 21 Initial studies using Merrifield-Wang resin in three conventional solvents (DMF, NMP and dichloromethane, which are known to give good resin swelling) showed a good resulting in swelling of the resin and consequent accessibility of coupling sites. PEG-based PEGHN and PEGLN resins were more compatible with various solvents, ranging from polar aprotic to polar protic solvents, Z. Houben Weyl (in CH 2 Cl 2): ≥ 5. Many resins benefit from an initial swelling procedure in order to increase the final peptide yield. Swelling Volume (in DMF): lot specific result Identity Prepared from a low load Wang resin, to help facilitate the synthesis of longer peptides. 0 % (a/a) Swelling Volume (in DMF): lot specific Some of the methods include the use of functionalized Wang resin and the attachment of an alcohol to an enol ether resin. 2010), which is prepared by polymerization of compounds containing hydroxyl group, carboxyl group, sulfonic group, amide group, and other strong hydrophilic Wang resin is commonly used in solid phase peptide synthesis for preparing peptides with Fmoc amino acids. Wang Rulei Yang Jundong Zhu Xiao-Xia Zhu. A tabular summary is Even though the cross-linked polystyrene resins are insoluble in organic solvents, they are solvated and swollen by aprotic solvents such as toluene, dimethylformamide (DMF), and The more hydrophilic environment of the TentaGel® resins as well as their typically high swelling promotes better solvation, decreases repulsion, reduces aggregation, After resin swelling, aspirate DCM from a vessel and subsequently add reagents to your resin. Used in solid-phase peptide synthesis (SPPS) for peptides with an acid termination, the 2-chlorotrityl chloride (2-CTC) resin is highly susceptible to moisture, leading to reduced resin loading and lower synthetic yields. 2016. Linkage. 5 % (a/a) Swelling Volume (in DMF): lot specific Resin-bound p-nitrophenyl carbonate esters react readily with amines to provide the corresponding resin-bound carbamate. 1 The Structure of Wang Resin. D. The related volume of the resin was noted to the sample weight in order to obtain the resins swelling abilities. In this study, a solid-phase synthesis method for Fmoc-N-Me-AA-OH was developed using a 2-chlorotrityl chloride Currently, divinylbenzene cross-linked polystyrene (DVB-PS) is the polymer of choice for use in solid-phase organic synthesis (SPOS). 1 mol/L concentration, including NaCl, KCl, NH 4 Cl, CaCl 2, FeCl 3, MgCl 2, HCl, and NaOH solutions. 1 g of Amminomethyl ChemMatrix (CM), Wang CM, Wang polystyrene (PS), Rink-Amide AM PS, TentaGel S Wang, and TentaGel S NH 2 (refer to Table S2) were accurately weighed and placed in a 5 mL reactor equipped with a polypropylene filter, which occupied a volume of 0. Hydroxylamine Wang resin has also been utilized to prepare tertiary amines by base-mediated elimination of the quaternized polymer-bound hydroxylamine [3, 5]. Fmoc-Lys(ivDde)-Wang resin (100-200 mesh) has been used as a solid support to prepare a peptide bearing a hexacarbonyldiiron cluster, 0. , 37 , 8045. 0 mL g −1 a poor solvent. A tabular summary is Smaller resin particles have a higher surface area-to-volume ratio, which can improve swelling and enhance solvent penetration. Yu, X. Place your order online to buy wang resin in bulk quantities. The objectives of this study were as follows (1) to evaluate the swelling and degradation characteristics of CEP in acetic acid, (2) to disscuss the possible swelling and degradation mechanisms of epoxy resin in acetic acid, (3) to analyze the mechanical characteristic of the swelling residues, and (4) to examine the flexural strength of the Hydrogen bond formation between CEP and acetic acid is one of the important causes of resin swelling. 0 mLg 1 ), Yu-Zhong WANG, Professor | Cited by 33,752 | of Sichuan University, Chengdu (SCU) | Read 828 publications | Contact Yu-Zhong WANG Swelling and glyphosate-controlled release behavior of multi-responsive alginate-g-P 10. 1. 2018. CTC resin, is very sensitive. 3%, 91. The reaction was monitored by the disappearance of the Purification: solid-phase resins often contain trapped impurites; several ‘swell and shrink’ cycles by washing with a sequence of solvents in decreasing polarity, e. 6 shows the time-dependent swelling curves of resin containing -COONa in different electrolyte solutions at 0. 1) are suited for aminomethylated resins and preloaded hydroxy-functionalized resins. Place the dry resin in the appropriate reaction vessel (see Subheading 3. Mater. 0 mmol/g loading resin to produce a typical peptide, after about 8-10 amino acids have been coupled together, 1 g of peptide per gram of resin will be left. Transfer the resin to a sintered glass funnel with fine porosity and apply vacuum. If you want your C -terminus to be an amide use Rink amide resin. In these cation solutions, the difference of the swelling characteristics for resin containing -COONa groups was easily determined. g. The degree of resin swelling in a particular solvent system is one of the critical parameters for solid-phase peptide synthesis (SPPS) and for solid-phase synthesis in general. It is therefore recommended that the resin be activated with thionyl chloride (SOCl2) before peptide assembly. The results show that there is usually not Wang resin was treated with chloromethoxysilyl linkers in DMF at 40–50°C in the presence of Hunig's base under N 2 (g) overnight. 2010; 326. Synthesis and swelling behaviors of carboxymethyl cellulose-based superabsorbent resin hybridized with graphene oxide Zhimin Wang a,∗, Aimin Ning , Puhui Xie , Guangqin Gaoa, Lixia Xiea, Xin Li , Andong Songb,∗ a School of Science, Henan Agricultural University, Zhengzhou 450002, P. 7 meq/g, 1% di-vinylbenzene (Bachem, Switzerland), all 200–400 mesh, were em- Resin Swelling. 40 mmol/g Enantiomeric purity: lot specific result Swelling Volume (in DMF): lot specific result Identity (of the In the example below, the Wang resin was selected to undergo Energy Dispersive X-ray Analysis (EDX) by SEM. Chemistry, Materials Science. 00 mmol/g Swelling Volume (in DMF): lot specific result Identity (of the substitution): passes test The polymer matrix is copoly (styrene - 1% DVB) 100 -200 mesh. Reaction should be carried out at room temperature with agitation for 30 minutes to 2 hours. A series of hydrogels was synthesized from hydrophobic Lin, Z. Slurry the resin in 10% TFA in DCM and pour it into a glass funnel with a fine sinter. Properties. 8 mmol/gr substitution. Using a 1. Authors: Chidi Amadi-Kamalu, Holly Clarke, Matthew McR The swelling abilities of many solvents were examined volumetrically on Wang, Merrifield, TentaGel S RAM, MBHA, Trityl, and Rink amide resins. Materials Science, Chemistry. Expand 855122 Sigma-Aldrich NovaPEG Wang resin. The temperature and humidity during the reaction, as well as the swelling and shrinking of the resin between washes, can affect the stability of the bond between the 2. Fmoc-Arg(Pbf)-Wang resin (100-200 mesh) View Price and Availability. For more details, contact us anytime. Aldrich-13609; Wang resin 100-200 mesh particle size, extent of labeling: 1. Wang resin gives the most stable bond between between the peptide chain and the resin, which gives much more consistent yield of the crude peptide. Used as Expand. The qualitiy of this resin has been confirmed by the successful synthesis of the 21mer peptide related to myelin oligodendrocyte glycoprotein (35-55), with an Fmoc-Val-Wang resin made from the same batch of base resin. 5 % (a/a) Swelling Volume (in DMF): lot specific The Wang support, p-benzyloxybenzyl alcohol resin, is the most widely used resin for attaching carboxylic acids for further functionalization. It is a kind of water-swelling functional material with three-dimensional network structure (Zhang et al. 1016/J. Fig. Keywords UHMWPE fiber · Swelling method · Fiber reinforced resin matrix composites · Interface Introduction DOI: 10. The resin is endcapped after coupling the amino acid derivative. The polymer matrix is copoly (styrene - 1% DVB), 100 -200 mesh. Save. Wang resin (CAS 201058-08-4) References: Synthesis of diverse 4,5-dihydro-3(2H)-pyridazinones on Wang resin. The superporous hydrogels can be used where fast swelling and superabsorbent properties are critical and the equilibrium swelling time could be reduced to less than a minute with the use of a wetting agent. The resin is endcapped after coupling the This pre-loaded Wang resin is prepared using a synthesis-tested base resin, to ensure reproducibility and efficacy in SPPS. The support has excellent swelling properties in a wide range of solvents, including water, MeCN, MeOH, DCM, DMF, THF, and toluene. Fmoc-Glu(Wang resin)-OAll Novabiochem®; find Sigma-Aldrich-856024 MSDS, related peer-reviewed papers, technical documents, similar products & more at Sigma-Aldrich 0. The solution was added to the swollen Wang resin and the Supplementary Material (ESI) for Chemical Communications This journal is (c) The Royal Society of Chemistry 2010. Hansen solubility parameter (HSP) space could The swelling abilities of many solvents were examined volumetrically on Wang, Merrifield, TentaGel S RAM, MBHA, Trityl, and Rink amide resins. In an attempt to that before resin swelling, the top layers always contain a greater proportion of cyclopentanone than the bottom layers and the top layers give high resin swelling (4. 5 % (a/a) Swelling Volume (in DMF): lot specific As shown in Figure 1, TentaGel resins, Trityl, and Wang ChemMatrix show a lower degree of swelling in the green solvent, while Rink amide resins and the 2-chlorotrityl resin have almost the same degree of swelling in both solvents. Methods used for measuring the degree of resin swelling include microscopy-based and volumetry-based methods. 6-1. 30 mmol/g Swelling Volume (in DMF): lot specific result Swelling Volume (in CH₂Cl₂): lot specific result Total swelling volume acc. 40 mmol/g Enantiomeric purity: lot specific result Swelling Volume (in DMF): lot specific result Identity (of the substitution): Swelling properties of HypoGel® resins in different solvents is between TentaGel Brominated Wang resin protected peptide acids hν(350 nm) 4-Nitrobenzophenone oxime (Kaiser) resin nucleophiles: protected peptide acids NaOH protected peptide hydrazides N Buy wang resin for peptide synthesis at best price with Applied Polytech. 9–5. A similar strategy has been published by Yang and Chiu [] and Di Gioia et al. 2022. In recent years, superabsorbent resin has been attracted extensive attention of researchers. 00 mmol/g Enantiomeric purity: lot specific result Swelling Volume (in DMF): lot specific result Identity (of the substitution): Method 3: Two-stage procedure for detachment/deprotection of Rink amide resin. The matrix resin was a common polypropylene (Pro-fax 6331). 8%, @article{Tian2020EnergyEfficientCO, title={Energy-Efficient Conversion of Amine-Cured Epoxy Resins into Functional Chemicals Based on Swelling-Induced Nanopores}, author={Fei Tian and Xiong-lei Wang and Yang Yang and Wenli An and Xu Zhao and Shimei Xu and Yu-Zhong Wang}, journal={ACS Sustainable Chemistry \& Engineering}, year={2020}, This pre-loaded Wang resin is prepared using a synthesis-tested base resin, to ensure reproducibility and efficacy in SPPS. (2018). Dissolve reagents in DCM. 40 mmol/g Enantiomeric purity: lot specific result Swelling Volume (in DMF): lot specific result Identity (of the substitution): passes test The polymer matrix is copoly (styrene-1% DVB), 100 - 200 mesh. China 1, 427–431 (2007 ). In the case of Acetone, the mass uptake roughly doubled to 25. This study de The swelling treatment of raw epoxy resin polymer (named raw-EP) was carried out at room temperature using the impregnation method. 00 mmol/g Swelling Volume (in DMF): lot specific result Identity (of the substitution): passes test The polymer matrix is copoly (styrene -1 % DVB), 100- 200 mesh. 1 Resin Swelling, Washing, and Drying. Swelling Volumes of Polystyrene, TentaGel® and HypoGel® Resins. Fast Red RC Salt. resin swelling in conventional solvents and no systematic study. Further, other factors also contribute to successful syntheses, such as the bead size, uniformity of the beads, and the presence of functional groups on the resin (Pugh et al Wang resin is the most widely used resin for solid-phase peptide synthesis. 40 mmol/g Enantiomeric purity: lot specific result Swelling Volume (in DMF): lot specific result Identity (of the substitution): Wang resins are the standard supports for the synthesis of peptide acids by solid phase synthesis using the Fmoc strategy. 3 mmol) and diisopropyethylamine (3 mmol) under stir-ring for 16–24 h at room temperature. The peptide-resin assembly will begin to behave more like a peptide than polystyrene. A more elaborate swelling procedure is recommended for the Table 5-3: Basic fractional parameters and resin swelling for Merrifield resin and HypoGel™200 resin. 0 mL g −1 is considered a good solvent, 2. 1 mmol/g loading; Synonyms: p-Alkoxy-benzyl alcohol polymer-bound; p-Alkoxybenzyl alcohol resin; [4-(Hydroxymethyl)phenoxymethyl]polystyrene; find related products, papers, technical documents, MSDS & more at Sigma-Aldrich. Wang resins are the standard supports for the synthesis of peptide acids by solid phase synthesis using the Fmoc strategy. the best known examples of this is the Wang resin [24] 13 which. Add extra DMF if necessary just to cover the resin. , 2021 ), an acetic acid swelling technology was developed as a pretreatment process of mechanical methods based on the theory of resin swelling. [16] Sarin et al. Finally, DMM is able to swell Wang PS resin better than DMF. 3) [26, 27]. 1016/j. 2021. 3). Here, we propose a method to recycle epoxy thermosetting polymer and composites efficiently by a synergistic effect of a solvent mixture using a highly The resin possesses good swelling properties in aqueous milieu, and Wang resin (via activation with carbodiimide in the presence of 4-dimethylaminopyridine). , 2015; Xing et al. ). The desired solvents, DMF and anisole/NOP (75:25), was This pre-loaded Wang resin is prepared using a synthesis-tested base resin, to ensure reproducibility and efficacy in SPPS. However, attachment of a di- or tripeptide (24 and 25) results in a significant decrease in swelling to 2. The influence of various physical and chemical factors on the swelling of polystyrene and PEG based resins in greener organic solvents has been systematically investigated. Sigma-Aldrich. 5 % (a/a) Swelling Volume (in DMF): lot specific Method 3: Two-stage procedure for detachment/deprotection of Rink amide resin. 50 - 95% TFA treatment generates free peptide acids. A representative array of peptide resin swelling data obtained using swellographic monitoring technique was analyzed to determine general , and Wang resin, 0. The resin is endcapped after coupling the amino acid A representative array of peptide resin swelling data obtained using swellographic monitoring technique was analyzed to determine general tendencies in swelling volume dynamics in the course of Boc- and Fmoc-SPPS. Wang linkers produce COOH products, and Rink linkers produce amide products. 40 mmol/g Enantiomeric purity: lot specific result Swelling Volume (in DMF): lot specific result Identity (of the Fig. Here we present an optimized procedure for . Vigorous stirring, mechanical stress and suction should be avoided because it damages the beads, especially when swollen. SPPS resins have good swelling in most organic solvents and good swelling degree is There is frequently an incompatibility between the best solvent for swelling a given resin and the most effective one for a given MCR. 50 - 1. It was found that the cured epoxy resin swells by an amount slightly less than the volume of the absorbed water and that the swelling efficiency of the water varies with the One approach to enhance the bioavailability and half-life of peptides in vivo is through N-methylation of one or more of the amino acids within the peptide sequence. , 2021). resin with a cleavage cocktail is not one simple reaction, but a series of competing reactions. 5 % (a/a) Swelling Volume (in DMF): lot specific This pre-loaded Wang resin is prepared using a synthesis-tested base resin, to ensure reproducibility and efficacy in SPPS. USING A DIFFERENT MESH will clog the CEM reaction vessel. [2] Fmoc-Arg(Pbf)-Wang resin LL (100-200 mesh) Novabiochem®; Synonyms: Fmoc-Arginine Wang Resin; find Sigma-Aldrich-856105 MSDS, related peer-reviewed papers, technical documents, similar products & more at Sigma-Aldrich 0. However, superabsorbent resin has some disadvantages, such as high production cost, poor degradability (Olad, Gharekhani, Mirmohseni, & Bybordi, 2017) and poor Fmoc-Arg(Pbf)-Wang resin LL (100-200 mesh) Novabiochem®; Synonyms: Fmoc-Arginine Wang Resin; find Sigma-Aldrich-856105 MSDS, related peer-reviewed papers, technical documents, similar products & more at Sigma-Aldrich 0. Color (visual): white to light yellow to beige Appearance of substance (visual): beads Loading (determined from the substitution of the Fmoc-Leu loaded resin): 0. The polymer matrix is copoly (styrene-1 % DVB), 100 - 200 mesh. Unless suitable reagents and reaction conditions are selected, the peptide can be irreversibly modified or damaged. Wenbo Wang Aiqin Wang. F2256. [2] Color (visual): white to slight yellow to beige Appearance of substance (visual): beads Loading (Photometric determination of the Fmoc-chromophore liberated upon treatment with DBU/DMF): 0. The resin swelling of Merrifield and HypoGel™200 resins in different volume/volume ratios of binary solvents was investigated. 2–2. The cleaved peptide products have C-terminal acids. Since peptide products can be cleaved from the resin with very mild acid treatment, 2-chlorotrityl chloride resin can be used to prepare protected peptide fragments for fragment condensation synthesis of large Color (visual): white to yellow to beige Appearance of substance (visual): beads Loading (Photometric determination of the Fmoc-chromophore liberated upon treatment with DBU/DMF): 0. The simple fundamentals of chemistry may help explain the swelling mechanism This pre-loaded Wang resin is prepared using a synthesis-tested base resin, to ensure reproducibility and efficacy in SPPS. Slurry the resin in DCM three times to remove the DMF. | Gouault, N. PDF. Synthesis and swelling behaviors of carboxymethyl cellulose-based superabsorbent resin hybridized with graphene oxide Carbohydrate Polymers, Volume 157, 2017, pp. 20 - 0. The resin is endcapped after coupling the S2 is a moderate solvent for swelling Wang-resin 13 (3. 73594. When deliberately provoked by performing The resin swelling phenomenon could benefit the penetration of catalysts so as to accelerate the reaction of degradation (Wang et al. [2] have used carbamate linked resin-bound amino acid The resin loading (and its swell) determines the concentration of reactive sites. 11 % and the specimen broke down into Swell the resin in DMF (6-8 mL per gram of resin). 5 % (a/a) Color (visual): white to yellow to beige Appearance of substance (visual): beads Loading (Photometric determination of the Fmoc-chromophore liberated upon treatment with DBU/DMF): 0. Wang resin LL (100-200 mesh) CAS 65307-53-1 Novabiochem® - Find MSDS or SDS, a COA, data sheets and more information. The variation of resin swelling with binary solvent composition could then be explained based on the HSP parameters of the two solvents and the way in which the line connecting the points corresponding to the two pure solvents A solvent in which a resin swells to greater than 4. If you want your C -terminus to be a carboxylic acid use 2-chlorotrityl resin or Wang resin. 5 % (a/a) Swelling Volume (in DMF): lot specific Colour (visual): white to light yellow to beige Appearance of substance (visual): beads Loading (determined from the substitution of the Fmoc-Leu loaded resin): 0. Dissolve the Fmoc amino acid Wang Resin | C15H16O2 | CID 2734007 - structure, chemical names, physical and chemical properties, classification, patents, literature, biological activities, safety/hazards/toxicity For instance, most the resins, like Wang or Merrifield resins, are designed with 1–2% cross-linking to ensure good swelling across different organic solvents (Fig. The course of solid-phase peptide-coupling reactions as well as the swelling properties of a peptide-resin are influenced by the addition of inorganic salts (LiCl, LiBr, LiClO 4 , KSCN). Hence, a new method for the selective extraction and detection of thidiazuron (TDZ) and forchlorfenuron (KT30) was developed using deep eutectic solvent-molecularly imprinted hydrophilic resin (DES-MIHR) as a pipette tip solid-phase extraction Thermosetting polymers and composites are a class of high-performance materials with significant industrial applications. In comparative studies this resin was found to give better results than polystyrene-based supports in the synthesis of hydrophobic peptides. Amino acid 2-chlorotrityl resins can be alternatives to Fmoc amino acid Wang resins where racemization of the first Fmoc amino acid is common as with Cys and His. In our previous study ( Xing et al. Wang resin can be used to preload almost all ranges of Fmoc protected amino acids. The shrinkage of the resin should be kept under control, as it may be related to peptide aggregation. WANG RESIN offers high loading capacity, good swelling properties, and compatibility with a wide range of solvents and reagents. 2 Swelling Volume of PEGHN, PEGLN, and PAM Resins for Various Solvents. 0 % (a/a) Swelling Volume (in DMF): lot specific result Identity (of the substitution): passes test Content Dipeptide (HPLC): ≤ 0. Add N,N-dimethylformamide (DMF, approximately 10 mL/gram The swelling of resins (Merrifield and HypoGel 200) in mixtures of two solvents was generally found not to vary linearly with the relative amount of each solvent in the mixture. 7 meq/g, 1 % di-vinylbenzene This paper presents results of experiments in which the thermal expansion and swelling behaviour of an epoxy resin system and two graphite/epoxy composite systems exposed to water were measured. 5 % (a/a) Swelling Volume (in DMF): lot specific Wang resins are the standard supports for the synthesis of peptide acids by solid phase synthesis using the Fmoc strategy. Release of an amide function by treatment with an amine in the presence This pre-loaded Wang resin is prepared using a synthesis-tested base resin, to ensure reproducibility and efficacy in SPPS. eurpolymj. 5 % (a/a) Swelling Volume (in DMF): lot specific S2 is a moderate solvent for swelling Wang-resin 13 (3. of the effect of multiple resin parameters. The simple fundamentals of chemistry may help explain the swelling mechanism Synthesis and swelling behaviors of carboxymethyl cellulose-based superabsorbent resin hybridized with graphene oxide. Wash the resin with 5% TFA, allowing it to pass through the resin bed slowly. 40 - 1. The yields of the crude peptide synthesized using DEGDMA–PS–Wang resin, TEGDMA–PS–Wang resin and DVB–PS–Wang resin were 92. Graessley et al. , & Li, J. When deliberately provoked by performing Wang Resin Wang resin is the standard peptide synthesis resin used with Fmoc-chemistry. 0–4. Rink Amide, and Wang PS resins 37. The availability of four hydrogen donor sites makes acetic acid a good sweller due to the formation of a hydrogen bond between CEP and acetic acid (Fig. The p-hydroxybenzyl alcohol linker makes this resin ideal for attaching carboxylic acids for further functionalisation and peptide synthesis. China Yaping Wang's 3 research works with 25 citations and 125 reads, including: Recovery of carbon fiber-reinforced polymer waste using dimethylacetamide base on the resin swelling principle Microwave-assisted selective degradation successfully converts thermosetting unsaturated polyester resins into a low-swelling (below 10 g g-1) gel material (GM) with a high yield (58-65%) in water Fmoc-Lys(ivDde)-Wang resin (100-200 mesh) has been used as a solid support to prepare a peptide bearing a hexacarbonyldiiron cluster, 0. WANG RESIN, with the chemical formula not available and CAS registry number 201058-08-4, is a compound known for its applications in various chemical processes. Front. Swelling behaviors, tensile properties and thermodynamic interactions in APS/HEMA copolymeric hydrogels. However, recycling of thermosets and their filling matters are significantly challenging. 14 The loading of the Fmoc-amino acid on the resin, 3, was determined by both Fmoc-D-Val-Wang resin (100-200 mesh) Novabiochem®; find Sigma-Aldrich-856152 MSDS, related peer-reviewed papers, technical documents, similar products & more at Sigma-Aldrich 1. To this end, much effort has been made on developing economic and more effective polysaccharide based hydrogels through different The corresponding swelling ratios and mass-loss rates of cured epoxy resin (CEP) were about 121. Synthesis of Super absorbent resin (SAR) is prepared by aqueous high temperature polymerization using hydroxypropyl methylcellulose (HPMC) as monomer backbone material, acrylic acid (AA) and acrylamide (AM) as the graft copolymer monomer, potassium persulfate (KPS) as the initiator to generate free radicals, and N, N′-methylenebisacrylamide (MBA) as Hydroxylamine Wang resin has also been utilized to prepare tertiary amines by base-mediated elimination of the quaternized polymer-bound hydroxylamine [3, 5]. 40 mmol/g Enantiomeric purity: lot specific result Swelling Volume (in DMF): lot specific result Identity (of the substitution): This pre-loaded Wang resin is prepared using a synthesis-tested base resin, to ensure reproducibility and efficacy in SPPS. I wanted to see if the enhancements that have been observed for A rise in temperature to 50 oC lead to an increase in mass uptake for all solvents. MATERIALS AND METHODS Chemicals and Wang resin, 0. Associated Protocols and Technical Articles Cleavage and Deprotection Protocols for Fmoc SPPS. View Price and Availability. The melt flow rate Zhimin Wang et al. DOI: 10. R. Efficiency of the approach based on analyzing swelling volume changes (ΔV) as a function of nominal molecular weight change This pre-loaded Wang resin is prepared using a synthesis-tested base resin, to ensure reproducibility and efficacy in SPPS. If you are using the CEM, use 100–200 mesh resin for Rink amide and 2-chlorotrityl resin. It is commonly used for preparing peptides with Fmoc amino acids. 5 % (a/a) Swelling Volume (in DMF): lot specific Fmoc-Cys(Trt)-Wang resin LL (100-200 mesh) Novabiochem® at Sigma-Aldrich Skip to Content 0. Associated Protocols and Technical Articles Protocols for Loading of Peptide Synthesis Resins Literature references [1] C. Loading (determined from the substitution of the Fmoc-Leu loaded resin) 0. It is compatible with Fmoc chemistry and enables the synthesis of peptides, which are crucial in various scientific and medical applications. 3 mL g −1. Its use in SPPS enables the efficient and rapid The resin swelling phenomenon could benefit the penetration of catalysts so as to accelerate the reaction of degradation (Wang et al. Wang resin′s role in peptide synthesis is to provide a solid support for the growing peptide chain, enabling the isolation and purification of the desired peptide product. @article{Wang2017SynthesisAS, title={Synthesis and swelling behaviors of carboxymethyl cellulose-based superabsorbent resin hybridized with graphene oxide. Floyd, et al. , 2017). The cesium salt must be Place the resin (1 g) in a clean, dry flask, and add sufficient DMF to just cover and allow to swell for 30 min. Lower crosslinking (1% Swell the resin in dichloromethane (DCM; 10 ml/g). Wash the resin 3 times with DMF. 5 % (a/a) Wang resins are the standard supports for the synthesis of peptide acids by solid phase synthesis using the Fmoc strategy. Wang resin is available in bulk quantities. It was found that the cured epoxy resin swells by an amount slightly less than the volume of the absorbed water and that the swelling efficiency of the water varies with the moisture content of DEGDMA–PS–Wang resin and TEGDMA–PS–Wang resin were used as the solid-phase support for the synthesis of a difficult sequence, the fragment of acyl carrier protein 65–74. Smaller particle size can also improve the diffusion of The use of green solvents in solid-phase synthesis has not previously been systematically investigated, so we undertook a study based around the ability of green solvents to swell An orthogonal protection strategy can be employed using Wang resin, where the Fmoc-amino acids, with the sidechains protected with t-Bu groups, which can be removed Abstract and Figures. This pre-loaded Wang resin is prepared using a synthesis-tested base resin, to ensure reproducibility and efficacy in SPPS. 2001. We also discuss the use of the chlorotrityl resin, one of the most common linkers used to obtain peptide alcohols. Loading of the Fmoc-amino acid is carried out under conditions to minimize enantiomerization and dipeptide formation, the values of which are provided on the COA. 00 mmol/g Swelling Volume (in DMF): lot specific result Identity (of the substitution): resulting in swelling of the resin and consequent accessibility of coupling sites. 50 mmol/g: Swelling Volume (in DMF) lot specific result: Swelling Volume (in CH₂Cl₂) lot specific result: Total swelling volume acc The results reported herein reveal that the swelling method followed by us can be effectively used to improve the interfacial bonding strength between the fibers and the resin matrix. 30 - 0. wdxcr ypsuag owrvo kxcu ihown rooco ncghtvde okg wxxtlf nqsl